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In vivo efficacy of sulphadoxine-pyrimethamine for the treatment of asymptomatic parasitaemia in pregnant women in Machinga District, Malawi

BACKGROUND: The effectiveness of sulphadoxine-pyrimethamine (SP) intermittent preventive treatment of malaria in pregnancy (IPTp) might be compromised by high prevalence of resistance-associated Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutations. As a...

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Detalles Bibliográficos
Autores principales: Gutman, Julie, Mwandama, Dyson, Wiegand, Ryan E, Abdallah, Joseph, Iriemenam, Nnaemeka C, Shi, Ya Ping, Mathanga, Don P, Skarbinski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435920/
https://www.ncbi.nlm.nih.gov/pubmed/25962439
http://dx.doi.org/10.1186/s12936-015-0710-7