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Delivering Oxidation Resistance-1 (OXR1) to Mouse Kidney by Genetic Modified Mesenchymal Stem Cells Exhibited Enhanced Protection against Nephrotoxic Serum Induced Renal Injury and Lupus Nephritis

OBJECTIVE: To elucidate the role of oxidation resistance 1 (OXR1) gene. Oxidative stress plays a pivotal role in pathogenesis of immune-mediated nephritis. Recently we identified oxidation resistance 1 (OXR1) is conventionally expressed in eukaryotes and has an ability to prevent oxidative damage ca...

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Detalles Bibliográficos
Autores principales: Li, Yajuan, Li, Wei, Liu, Chu, Yan, Mei, Raman, Indu, Du, Yong, Fang, Xiangdong, Zhou, Xin J., Mohan, Chandra, Li, Quan-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435960/
https://www.ncbi.nlm.nih.gov/pubmed/25995969
http://dx.doi.org/10.4172/2157-7633.1000231