Cargando…

Delivering Oxidation Resistance-1 (OXR1) to Mouse Kidney by Genetic Modified Mesenchymal Stem Cells Exhibited Enhanced Protection against Nephrotoxic Serum Induced Renal Injury and Lupus Nephritis

OBJECTIVE: To elucidate the role of oxidation resistance 1 (OXR1) gene. Oxidative stress plays a pivotal role in pathogenesis of immune-mediated nephritis. Recently we identified oxidation resistance 1 (OXR1) is conventionally expressed in eukaryotes and has an ability to prevent oxidative damage ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yajuan, Li, Wei, Liu, Chu, Yan, Mei, Raman, Indu, Du, Yong, Fang, Xiangdong, Zhou, Xin J., Mohan, Chandra, Li, Quan-Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435960/ https://www.ncbi.nlm.nih.gov/pubmed/25995969 http://dx.doi.org/10.4172/2157-7633.1000231

Ejemplares similares

Kallikrein Transduced Mesenchymal Stem Cells Protect against Anti-GBM Disease and Lupus Nephritis by Ameliorating Inflammation and Oxidative Stress
por: Li, Yajuan, et al.
Publicado: (2013)

Biomarker Profiling for Lupus Nephritis
por: Li, Yajuan, et al.
Publicado: (2013)

Glutathione S-transferase Mu 2-transduced mesenchymal stem cells ameliorated anti-glomerular basement membrane antibody-induced glomerulonephritis by inhibiting oxidation and inflammation
por: Li, Yajuan, et al.
Publicado: (2014)

Lupus nephritis: current update
por: Saxena, Ramesh, et al.
Publicado: (2011)

The antioxidant protein Oxr1 influences aspects of mitochondrial morphology
por: Wu, Yixing, et al.
Publicado: (2016)

Preventing Neurodegeneration by Controlling Oxidative Stress: The Role of OXR1
por: Volkert, Michael R., et al.
Publicado: (2020)

Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration
por: Oliver, Peter L., et al.
Publicado: (2011)

Lupus nephritis - alarmins may sound the alarm?
por: Wu, Tianfu, et al.
Publicado: (2012)

Insulin-Like Growth Factor Binding Protein-4 as a Marker of Chronic Lupus Nephritis
por: Wu, Tianfu, et al.
Publicado: (2016)

Zebrafish Oxr1a Knockout Reveals Its Role in Regulating Antioxidant Defenses and Aging
por: Xu, Hao, et al.
Publicado: (2020)

OXR1 STABILIZES THE RETROMER TO EXTEND LIFESPAN AND NEURONAL HEALTH BY DIETARY RESTRICTION
por: Wilson, Kenneth, et al.
Publicado: (2022)

Urinary angiostatin, CXCL4 and VCAM-1 as biomarkers of lupus nephritis
por: Mok, Chi Chiu, et al.
Publicado: (2018)

Mobile health apps for systemic lupus erythematosus and lupus nephritis: a critical appraisal
por: Ramasamy, Akshara, et al.
Publicado: (2022)

Age-Related Neuroprotection by Dietary Restriction Requires OXR1-Mediated Retromer Function
por: Wilson, Kenneth, et al.
Publicado: (2021)

Lack of Effect of a Single Injection of Human C-Reactive Protein on Murine Lupus or Nephrotoxic Nephritis
por: Carlucci, Francesco, et al.
Publicado: (2010)

Effect of Sex Hormones on Nephrotoxic Nephritis in the Rat
por: Le Compte, Philip M.
Publicado: (1944)

Immunomodulatory Activity of Mesenchymal Stem Cells in Lupus Nephritis: Advances and Applications
por: Li, Jicui, et al.
Publicado: (2022)

Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations
por: Finelli, Mattéa J., et al.
Publicado: (2015)

Severe Nephrotoxic Nephritis following Conditional and Kidney-Specific Knockdown of Stanniocalcin-1
por: Huang, Luping, et al.
Publicado: (2015)

A Systematic Review of Interpathologist Agreement in Histologic Classification of Lupus Nephritis
por: Dasari, Shobha, et al.
Publicado: (2019)

Current Insights on Biomarkers in Lupus Nephritis: A Systematic Review of the Literature
por: Palazzo, Leonardo, et al.
Publicado: (2022)

Urine proteomic insights from the belimumab in lupus nephritis trial
por: Weeding, Emma, et al.
Publicado: (2022)

Discovery of Novel Circulating Immune Complexes in Lupus Nephritis Using Immunoproteomics
por: Tang, Chenling, et al.
Publicado: (2022)

A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS
por: Cochrane, Charles G., et al.
Publicado: (1965)

EXPERIMENTAL GLOMERULONEPHRITIS : IV. PARTICIPATION OF COMPLEMENT IN NEPHROTOXIC NEPHRITIS
por: Unanue, Emil, et al.
Publicado: (1964)

THE EFFECT OF DIETARY PROTEIN ON THE COURSE OF NEPHROTOXIC NEPHRITIS IN RATS
por: Farr, Lee E., et al.
Publicado: (1939)

The effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis
por: Hackl, A., et al.
Publicado: (2023)

Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis
por: Liu, Kevin X., et al.
Publicado: (2015)

Urine VCAM-1 as a marker of renal pathology activity index in lupus nephritis
por: Singh, Sandeep, et al.
Publicado: (2012)

TNIP1/ABIN1 and lupus nephritis: review
por: Brady, Makayla P, et al.
Publicado: (2020)

NEPHROTOXIC SERUM NEPHRITIS IN RATS : I. DISTRIBUTION AND SPECIFICITY OF THE ANTIGEN RESPONSIBLE FOR THE PRODUCTION OF NEPHROTOXIC ANTIBODIES
por: Baxter, James H., et al.
Publicado: (1956)

The Anopheles gambiae Oxidation Resistance 1 (OXR1) Gene Regulates Expression of Enzymes That Detoxify Reactive Oxygen Species
por: Jaramillo-Gutierrez, Giovanna, et al.
Publicado: (2010)

The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins
por: Durand, Mathieu, et al.
Publicado: (2007)

Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis
por: Qin, Ling, et al.
Publicado: (2019)

Structural/functional analysis of the human OXR1 protein: identification of exon 8 as the anti-oxidant encoding function
por: Murphy, Kenan C, et al.
Publicado: (2012)

Oxidative stress protein Oxr1 promotes V‐ATPase holoenzyme disassembly in catalytic activity‐independent manner
por: Khan, Md. Murad, et al.
Publicado: (2021)

Tubulointerstitial lesions converted into lupus nephritis
por: Yang, Ning, et al.
Publicado: (2019)

EXPERIMENTAL GLOMERULONEPHRITIS : VI. THE AUTOLOGOUS PHASE OF NEPHROTOXIC SERUM NEPHRITIS
por: Unanue, Emil R., et al.
Publicado: (1965)

NEPHROTOXIC NEPHRITIS IN RATS : EVIDENCE FOR THE GLOMERULAR ORIGIN OF THE KIDNEY ANTIGEN
por: Solomon, David H., et al.
Publicado: (1949)

Murine Nephrotoxic Nephritis as a Model of Chronic Kidney Disease
por: Ougaard, M. K. E., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_g65jgtnngvp4g7f6lnr65m13u3