Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes

West Nile virus (WNV) is an emerging neuroinvasive flavivirus that now causes significant morbidity and mortality worldwide. The innate and adaptive immune responses to WNV infection have been well studied in C57BL/6J inbred mice, but this model lacks the variations in susceptibility, immunity, and...

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Detalles Bibliográficos
Autores principales: Graham, Jessica B., Thomas, Sunil, Swarts, Jessica, McMillan, Aimee A., Ferris, Martin T., Suthar, Mehul S., Treuting, Piper M., Ireton, Renee, Gale, Michael, Lund, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436067/
https://www.ncbi.nlm.nih.gov/pubmed/25944860
http://dx.doi.org/10.1128/mBio.00493-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436067/
https://www.ncbi.nlm.nih.gov/pubmed/25944860
http://dx.doi.org/10.1128/mBio.00493-15

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