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Identification of Quorum-Sensing Inhibitors Disrupting Signaling between Rgg and Short Hydrophobic Peptides in Streptococci

Bacteria coordinate a variety of social behaviors, important for both environmental and pathogenic bacteria, through a process of intercellular chemical signaling known as quorum sensing (QS). As microbial resistance to antibiotics grows more common, a critical need has emerged to develop novel anti...

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Detalles Bibliográficos
Autores principales: Aggarwal, Chaitanya, Jimenez, Juan Cristobal, Lee, Hyun, Chlipala, George E., Ratia, Kiira, Federle, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436074/
https://www.ncbi.nlm.nih.gov/pubmed/25968646
http://dx.doi.org/10.1128/mBio.00393-15