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Partial protein domains: evolutionary insights and bioinformatics challenges

Protein domains are generally thought to correspond to units of evolution. New research raises questions about how such domains are defined with bioinformatics tools and sheds light on how evolution has enabled partial domains to be viable.

Detalles Bibliográficos
Autores principales: Kelley, Lawrence A, Sternberg, Michael JE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436111/
https://www.ncbi.nlm.nih.gov/pubmed/25986583
http://dx.doi.org/10.1186/s13059-015-0663-8