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Oxygen Concentration Controls Epigenetic Effects in Models of Familial Paraganglioma
Familial paraganglioma (PGL) is a rare neuroendocrine cancer associated with defects in the genes encoding the subunits of succinate dehydrogenase (SDH), a tricarboxylic acid (TCA) cycle enzyme. For unknown reasons, a higher prevalence of PGL has been reported for humans living at higher altitude, w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436181/ https://www.ncbi.nlm.nih.gov/pubmed/25985299 http://dx.doi.org/10.1371/journal.pone.0127471 |