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Inflammasome Priming Is Similar for Francisella Species That Differentially Induce Inflammasome Activation

Inflammasome activation is a two-step process where step one, priming, prepares the inflammasome for its subsequent activation, by step two. Classically step one can be induced by LPS priming followed by step two, high dose ATP. Furthermore, when IL-18 processing is used as the inflammasome readout,...

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Detalles Bibliográficos
Autores principales: Ghonime, Mohammed G., Mitra, Srabani, Eldomany, Ramadan A., Wewers, Mark D., Gavrilin, Mikhail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436270/
https://www.ncbi.nlm.nih.gov/pubmed/25993107
http://dx.doi.org/10.1371/journal.pone.0127278