Direct Interaction of CD40 on Tumor Cells with CD40L on T Cells Increases the Proliferation of Tumor Cells by Enhancing TGF-β Production and Th17 Differentiation

It has recently been reported that the CD40-CD40 ligand (CD40L) interaction is important in Th17 development. In addition, transforming growth factor—beta (TGF-β) promotes tumorigenesis as an immunosuppressive cytokine and is crucial in the development of Th17 cells. This study investigated the role...

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Detalles Bibliográficos
Autores principales: Kim, Hyemin, Kim, Yejin, Bae, Seyeon, Kong, Joo Myoung, Choi, Jiwon, Jang, Mirim, Choi, Jiyea, Hong, Jun-man, Hwang, Young-il, Kang, Jae Seung, Lee, Wang Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436336/
https://www.ncbi.nlm.nih.gov/pubmed/25992978
http://dx.doi.org/10.1371/journal.pone.0125742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436336/
https://www.ncbi.nlm.nih.gov/pubmed/25992978
http://dx.doi.org/10.1371/journal.pone.0125742

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