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Robust Linear Models for Cis-eQTL Analysis

Expression Quantitative Trait Loci (eQTL) analysis enables characterisation of functional genetic variation influencing expression levels of individual genes. In outbread populations, including humans, eQTLs are commonly analysed using the conventional linear model, adjusting for relevant covariates...

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Detalles Bibliográficos
Autores principales: Rantalainen, Mattias, Lindgren, Cecilia M., Holmes, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436354/
https://www.ncbi.nlm.nih.gov/pubmed/25992607
http://dx.doi.org/10.1371/journal.pone.0127882