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Cilostazol Attenuates Ovariectomy-Induced Bone Loss by Inhibiting Osteoclastogenesis

BACKGROUND: Cilostazol has been reported to alleviate the metabolic syndrome induced by increased intracellular adenosine 3’,5’-cyclic monophosphate (cAMP) levels, which is also associated with osteoclast (OC) differentiation. We hypothesized that bone loss might be attenuated via an action on OC by...

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Detalles Bibliográficos
Autores principales: Ke, Ke, Safder, Ali Muhammad, Sul, Ok-Joo, Suh, Jae-Hee, Joe, Yeonsoo, Chung, Hun-Taeg, Choi, Hye-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436362/
https://www.ncbi.nlm.nih.gov/pubmed/25992691
http://dx.doi.org/10.1371/journal.pone.0124869