Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model

Transforming growth factor-β (TGF-β) has a dual role in tumorigenesis, acting as either a tumor suppressor or as a pro-oncogenic factor in a context-dependent manner. Although TGF-β antagonists have been proposed as anti-metastatic therapies for patients with advanced stage cancer, how TGF-β mediate...

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Detalles Bibliográficos
Autores principales: Sato, Misako, Matsubara, Tsutomu, Adachi, Jun, Hashimoto, Yuuki, Fukamizu, Kazuna, Kishida, Marina, Yang, Yu-an, Wakefield, Lalage M., Tomonaga, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436378/
https://www.ncbi.nlm.nih.gov/pubmed/25993439
http://dx.doi.org/10.1371/journal.pone.0126483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436378/
https://www.ncbi.nlm.nih.gov/pubmed/25993439
http://dx.doi.org/10.1371/journal.pone.0126483

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