Cargando…

Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model

Transforming growth factor-β (TGF-β) has a dual role in tumorigenesis, acting as either a tumor suppressor or as a pro-oncogenic factor in a context-dependent manner. Although TGF-β antagonists have been proposed as anti-metastatic therapies for patients with advanced stage cancer, how TGF-β mediate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sato, Misako, Matsubara, Tsutomu, Adachi, Jun, Hashimoto, Yuuki, Fukamizu, Kazuna, Kishida, Marina, Yang, Yu-an, Wakefield, Lalage M., Tomonaga, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436378/ https://www.ncbi.nlm.nih.gov/pubmed/25993439 http://dx.doi.org/10.1371/journal.pone.0126483

Ejemplares similares

Data for proteomic analysis of ATP-binding proteins and kinase inhibitor target proteins using an ATP probe
por: Adachi, Jun, et al.
Publicado: (2015)

Quantitative proteomic analysis of cultured skin fibroblast cells derived from patients with triglyceride deposit cardiomyovasculopathy
por: Hara, Yasuhiro, et al.
Publicado: (2013)

Synergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide
por: Chen, Xin, et al.
Publicado: (2014)

Regulation of Tumor Immune Surveillance and Tumor Immune Subversion by TGF-β
por: Park, Hae-Young, et al.
Publicado: (2009)

Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling
por: Sato-Matsubara, Misako, et al.
Publicado: (2017)

Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics
por: Shiromizu, Takashi, et al.
Publicado: (2017)

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium
por: Flanders, Kathleen C., et al.
Publicado: (2016)

Capillary nano-immunoassays: advancing quantitative proteomics analysis, biomarker assessment, and molecular diagnostics
por: Chen, Jin-Qiu, et al.
Publicado: (2015)

A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland
por: Kohn, Ethan A, et al.
Publicado: (2010)

Metabolic Engineering of Shikimic Acid-Producing Corynebacterium glutamicum From Glucose and Cellobiose Retaining Its Phosphotransferase System Function and Pyruvate Kinase Activities
por: Sato, Naoki, et al.
Publicado: (2020)

Automated Proteomics Sample Preparation of Phosphatidylserine-Positive Extracellular Vesicles from Human Body Fluids
por: Muraoka, Satoshi, et al.
Publicado: (2022)

Cell-free synthesis of stable isotope-labeled internal standards for targeted quantitative proteomics
por: Narumi, Ryohei, et al.
Publicado: (2018)

Comprehensive proteomic profiling of plasma and serum phosphatidylserine-positive extracellular vesicles reveals tissue-specific proteins
por: Muraoka, Satoshi, et al.
Publicado: (2022)

In‐depth proteomics reveals the characteristic developmental profiles of early lung adenocarcinoma with epidermal growth factor receptor mutation
por: Dai, Tomoko, et al.
Publicado: (2023)

Effective Chemoimmunotherapy with Anti-TGFβ Antibody and Cyclophosphamide in a Mouse Model of Breast Cancer
por: Chen, Xin, et al.
Publicado: (2014)

Delineating Genetic Alterations for Tumor Progression in the MCF10A Series of Breast Cancer Cell Lines
por: Kadota, Mitsutaka, et al.
Publicado: (2010)

Anti-fibrotic treatments for chronic liver diseases: The present and the future
por: Odagiri, Naoshi, et al.
Publicado: (2021)

Brightfield Proximity Ligation Assay Reveals Both Canonical and Mixed Transforming Growth Factor-β/Bone Morphogenetic Protein Smad Signaling Complexes in Tissue Sections
por: Flanders, Kathleen C., et al.
Publicado: (2014)

Transforming growth factor-β and breast cancer: Lessons learned from genetically altered mouse models
por: Wakefield, Lalage M, et al.
Publicado: (2000)

Deep Phospho- and Phosphotyrosine Proteomics Identified Active Kinases and Phosphorylation Networks in Colorectal Cancer Cell Lines Resistant to Cetuximab
por: Abe, Yuichi, et al.
Publicado: (2017)

Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer
por: Staudacher, Jonas J., et al.
Publicado: (2017)

Vitamin B1 Supports the Differentiation of T Cells through TGF-β Superfamily Production in Thymic Stromal Cells
por: Hirata, So-ichiro, et al.
Publicado: (2020)

Effects of Dietary Defatted Meat Species on Metabolomic Profiles of Murine Liver, Gastrocnemius Muscle, and Cecal Content
por: Nakata, Rise, et al.
Publicado: (2020)

Transient Tumor-Fibroblast Interactions Increase Tumor Cell Malignancy by a TGF-β Mediated Mechanism in a Mouse Xenograft Model of Breast Cancer
por: Stuelten, Christina H., et al.
Publicado: (2010)

Possible involvement of TGF-β-SMAD-mediated epithelial-mesenchymal transition in pro-metastatic property of PAX6
por: Jin, Meng, et al.
Publicado: (2020)

Characterization of the MDSC Proteome Associated with Metastatic Murine Mammary Tumors Using Label-Free Mass Spectrometry and Shotgun Proteomics
por: Boutté, Angela M., et al.
Publicado: (2011)

A large‐scale targeted proteomics of plasma extracellular vesicles shows utility for prognosis prediction subtyping in colorectal cancer
por: Kasahara, Keiko, et al.
Publicado: (2022)

TGFβ selects for pro‐stemness over pro‐invasive phenotypes during cancer cell epithelial–mesenchymal transition
por: Tsubakihara, Yutaro, et al.
Publicado: (2022)

Generation of a monoclonal antibody recognizing the CEACAM glycan structure and inhibiting adhesion using cancer tissue-originated spheroid as an antigen
por: Sato, Yumi, et al.
Publicado: (2016)

Corrigendum: Generation of a monoclonal antibody recognizing the CEACAM glycan structure and inhibiting adhesion using cancer tissue-originated spheroid as an antigen
por: Sato, Yumi, et al.
Publicado: (2016)

Membrane Proteomics to Understand Enhancement Effects of Millimeter-Wave Irradiation on Wheat Root under Flooding Stress
por: Komatsu, Setsuko, et al.
Publicado: (2023)

Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON
por: Kuga, Takahisa, et al.
Publicado: (2016)

Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation
por: Takeuchi, Masao, et al.
Publicado: (2015)

Correction: Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation
por: Takeuchi, Masao, et al.
Publicado: (2015)

The Pro-inflammatory Role of TGFβ1: A Paradox?
por: Han, Gangwen, et al.
Publicado: (2012)

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer
por: Sato, Misako, et al.
Publicado: (2014)

Altered proTGFα/cleaved TGFα ratios offer new therapeutic strategies in renal carcinoma
por: García-Alonso, Sara, et al.
Publicado: (2021)

Pax6 interacts with SPARC and TGF-β in murine eyes
por: Shubham, Kumar, et al.
Publicado: (2012)

Involvement of TGFβ-Induced Phosphorylation of the PTEN C-Terminus on TGFβ-Induced Acquisition of Malignant Phenotypes in Lung Cancer Cells
por: Aoyama, Daisuke, et al.
Publicado: (2013)

Nephrectomy for Metastatic Kidney Tumor in Patients with Differentiated Thyroid Cancer: A Report of Two Cases
por: Yamazaki, Haruhiko, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rlrr684kn32nkejs002nupcoog