Electrophysiological characterization of activation state-dependent Ca(v)2 channel antagonist TROX-1 in spinal nerve injured rats

Prialt, a synthetic version of Ca(v)2.2 antagonist ω-conotoxin MVIIA derived from Conus magus, is the first clinically approved voltage-gated calcium channel blocker for refractory chronic pain. However, due to the narrow therapeutic window and considerable side effects associated with systemic dosi...

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Detalles Bibliográficos
Autores principales: Patel, R., Rutten, K., Valdor, M., Schiene, K., Wigge, S., Schunk, S., Damann, N., Christoph, T., Dickenson, A.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436437/
https://www.ncbi.nlm.nih.gov/pubmed/25839150
http://dx.doi.org/10.1016/j.neuroscience.2015.03.057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436437/
https://www.ncbi.nlm.nih.gov/pubmed/25839150
http://dx.doi.org/10.1016/j.neuroscience.2015.03.057

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