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Administration of 4-(α-L-Rhamnosyloxy)-benzyl Isothiocyanate Delays Disease Phenotype in SOD1(G93A) Rats: A Transgenic Model of Amyotrophic Lateral Sclerosis

4-(α-L-Rhamnosyloxy)-benzyl glucosinolate (glucomoringin, GMG) is a compound found in Moringa oleifera seeds. Myrosinase-catalyzed hydrolysis at neutral pH of GMG releases the biologically active compound 4-(α-L-rhamnosyloxy)-benzyl isothiocyanate (GMG-ITC). The present study was designed to test th...

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Detalles Bibliográficos
Autores principales: Galuppo, Maria, Giacoppo, Sabrina, Iori, Renato, De Nicola, Gina Rosalinda, Bramanti, Placido, Mazzon, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436451/
https://www.ncbi.nlm.nih.gov/pubmed/26075221
http://dx.doi.org/10.1155/2015/259417