A Double-Switch Cell Fusion-Inducible Transgene Expression System for Neural Stem Cell-Based Antiglioma Gene Therapy

Recent progress in neural stem cell- (NSC-) based tumor-targeted gene therapy showed that NSC vectors expressing an artificially engineered viral fusogenic protein, VSV-G H162R, could cause tumor cell death specifically under acidic tumor microenvironment by syncytia formation; however, the killing...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Yumei, Zhu, Detu, Lam, Dang Hoang, Huang, Juan, Tang, Yi, Luo, Xitu, Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436471/
https://www.ncbi.nlm.nih.gov/pubmed/26074975
http://dx.doi.org/10.1155/2015/649080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436471/
https://www.ncbi.nlm.nih.gov/pubmed/26074975
http://dx.doi.org/10.1155/2015/649080

Ejemplares similares