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Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction

Objectives. Low survival rate of mesenchymal stem cells (MSCs) severely limited the therapeutic efficacy of cell therapy in the treatment of myocardial infarction (MI). Bcl-xL genetic modification might enhance MSC survival after transplantation. Methods. Adult rat bone marrow MSCs were modified wit...

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Detalles Bibliográficos
Autores principales: Xue, Xiaodong, Liu, Yu, Zhang, Jian, Liu, Tao, Yang, Zhonglu, Wang, Huishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436513/
https://www.ncbi.nlm.nih.gov/pubmed/26074971
http://dx.doi.org/10.1155/2015/176409