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Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels
How nature discriminates sodium from calcium ions in eukaryotic channels has been difficult to resolve because they contain four homologous, but markedly different repeat domains. We glean clues from analyzing the changing pore region in sodium, calcium and NALCN channels, from single-cell eukaryote...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436565/ https://www.ncbi.nlm.nih.gov/pubmed/26042044 http://dx.doi.org/10.3389/fphys.2015.00153 |