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Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels

How nature discriminates sodium from calcium ions in eukaryotic channels has been difficult to resolve because they contain four homologous, but markedly different repeat domains. We glean clues from analyzing the changing pore region in sodium, calcium and NALCN channels, from single-cell eukaryote...

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Detalles Bibliográficos
Autores principales:	Stephens, Robert F., Guan, W., Zhorov, Boris S., Spafford, J. David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436565/ https://www.ncbi.nlm.nih.gov/pubmed/26042044 http://dx.doi.org/10.3389/fphys.2015.00153

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