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Mutations associated with Dent's disease affect gating and voltage dependence of the human anion/proton exchanger ClC-5

Dent's disease is associated with impaired renal endocytosis and endosomal acidification. It is linked to mutations in the membrane chloride/proton exchanger ClC-5; however, a direct link between localization in the protein and functional phenotype of the mutants has not been established until...

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Detalles Bibliográficos
Autor principal:	Alekov, Alexi K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436585/ https://www.ncbi.nlm.nih.gov/pubmed/26042048 http://dx.doi.org/10.3389/fphys.2015.00159

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