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oskar RNA plays multiple noncoding roles to support oogenesis and maintain integrity of the germline/soma distinction

The Drosophila oskar (osk) mRNA is unusual in that it has both coding and noncoding functions. As an mRNA, osk encodes a protein required for embryonic patterning and germ cell formation. Independent of that function, the absence of osk mRNA disrupts formation of the karyosome and blocks progression...

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Detalles Bibliográficos
Autores principales: Kanke, Matt, Jambor, Helena, Reich, John, Marches, Brittany, Gstir, Ronald, Ryu, Young Hee, Ephrussi, Anne, Macdonald, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436663/
https://www.ncbi.nlm.nih.gov/pubmed/25862242
http://dx.doi.org/10.1261/rna.048298.114