Role of six single nucleotide polymorphisms, risk factors in coronary disease, in OLR1 alternative splicing

The OLR1 gene encodes the oxidized low-density lipoprotein receptor (LOX-1), which is responsible for the cellular uptake of oxidized LDL (Ox-LDL), foam cell formation in atheroma plaques and atherosclerotic plaque rupture. Alternative splicing (AS) of OLR1 exon 5 generates two protein isoforms with...

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Detalles Bibliográficos
Autores principales: Tejedor, J. Ramón, Tilgner, Hagen, Iannone, Camilla, Guigó, Roderic, Valcárcel, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436670/
https://www.ncbi.nlm.nih.gov/pubmed/25904137
http://dx.doi.org/10.1261/rna.049890.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436670/
https://www.ncbi.nlm.nih.gov/pubmed/25904137
http://dx.doi.org/10.1261/rna.049890.115

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