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Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt

The collecting system of the kidney develops from the ureteric bud (UB), which undergoes branching morphogenesis, a process regulated by multiple factors, including integrin–extracellular matrix interactions. The laminin (LM)-binding integrin α3β1 is crucial for this developmental program; however,...

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Detalles Bibliográficos
Autores principales: Yazlovitskaya, Eugenia M., Tseng, Hui-Yuan, Viquez, Olga, Tu, Tianxiang, Mernaugh, Glenda, McKee, Karen K., Riggins, Karen, Quaranta, Vito, Pathak, Amrita, Carter, Bruce D., Yurchenco, Peter, Sonnenberg, Arnoud, Böttcher, Ralph T., Pozzi, Ambra, Zent, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436831/
https://www.ncbi.nlm.nih.gov/pubmed/25808491
http://dx.doi.org/10.1091/mbc.E14-07-1203