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The AP2 clathrin adaptor protein complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of Caenorhabditis elegans

Regulation of glutamate receptor (GluR) abundance at synapses by clathrin-mediated endocytosis can control synaptic strength and plasticity. We take advantage of viable, null mutations in subunits of the clathrin adaptor protein 2 (AP2) complex in Caenorhabditis elegans to characterize the in vivo r...

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Detalles Bibliográficos
Autores principales: Garafalo, Steven D., Luth, Eric S., Moss, Benjamin J., Monteiro, Michael I., Malkin, Emily, Juo, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436833/
https://www.ncbi.nlm.nih.gov/pubmed/25788288
http://dx.doi.org/10.1091/mbc.E14-06-1048