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A preclinical study demonstrating the efficacy of nilotinib in inhibiting the growth of pediatric high-grade glioma

Solid tumors arising from malignant transformation of glial cells are one of the leading causes of central nervous system tumor-related death in children. Recurrence in spite of rigorous surgical and chemoradiation therapies remains a major hurdle in management of these tumors. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Au, Karolyn, Singh, Sanjay K., Burrell, Kelly, Sabha, Nesrin, Hawkins, Cynthia, Huang, Annie, Zadeh, Gelareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436849/
https://www.ncbi.nlm.nih.gov/pubmed/25732621
http://dx.doi.org/10.1007/s11060-015-1744-y