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Optimally choosing PWM motif databases and sequence scanning approaches based on ChIP-seq data

BACKGROUND: For many years now, binding preferences of Transcription Factors have been described by so called motifs, usually mathematically defined by position weight matrices or similar models, for the purpose of predicting potential binding sites. However, despite the availability of thousands of...

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Detalles Bibliográficos
Autores principales: Dabrowski, Michal, Dojer, Norbert, Krystkowiak, Izabella, Kaminska, Bozena, Wilczynski, Bartek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436866/
https://www.ncbi.nlm.nih.gov/pubmed/25927199
http://dx.doi.org/10.1186/s12859-015-0573-5