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Optimally choosing PWM motif databases and sequence scanning approaches based on ChIP-seq data
BACKGROUND: For many years now, binding preferences of Transcription Factors have been described by so called motifs, usually mathematically defined by position weight matrices or similar models, for the purpose of predicting potential binding sites. However, despite the availability of thousands of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436866/ https://www.ncbi.nlm.nih.gov/pubmed/25927199 http://dx.doi.org/10.1186/s12859-015-0573-5 |