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The role of molecular chaperones in clathrin mediated vesicular trafficking

The discovery that the 70 kD “uncoating ATPase,” which removes clathrin coats from vesicles after endocytosis, is the constitutively expressed Hsc70 chaperone was a surprise. Subsequent work, however, revealed that uncoating is an archetypal Hsp70 reaction: the cochaperone auxilin, which contains a...

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Detalles Bibliográficos
Autores principales: Sousa, Rui, Lafer, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436892/
https://www.ncbi.nlm.nih.gov/pubmed/26042225
http://dx.doi.org/10.3389/fmolb.2015.00026