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The role of molecular chaperones in clathrin mediated vesicular trafficking
The discovery that the 70 kD “uncoating ATPase,” which removes clathrin coats from vesicles after endocytosis, is the constitutively expressed Hsc70 chaperone was a surprise. Subsequent work, however, revealed that uncoating is an archetypal Hsp70 reaction: the cochaperone auxilin, which contains a...
Autores principales: | Sousa, Rui, Lafer, Eileen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436892/ https://www.ncbi.nlm.nih.gov/pubmed/26042225 http://dx.doi.org/10.3389/fmolb.2015.00026 |
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