Cargando…

Structure of Slitrk2–PTPδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion

Selective binding between pre- and postsynaptic adhesion molecules can induce synaptic differentiation. Here we report the crystal structure of a synaptogenic trans-synaptic adhesion complex between Slit and Trk-like family member 2 (Slitrk2) and receptor protein tyrosine phosphatase (RPTP) δ. The s...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamagata, Atsushi, Sato, Yusuke, Goto-Ito, Sakurako, Uemura, Takeshi, Maeda, Asami, Shiroshima, Tomoko, Yoshida, Tomoyuki, Fukai, Shuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437028/
https://www.ncbi.nlm.nih.gov/pubmed/25989451
http://dx.doi.org/10.1038/srep09686