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Brain SERT Expression of Male Rats Is Reduced by Aging and Increased by Testosterone Restitution

In preclinical and clinical studies aging has been associated with a deteriorated response to antidepressant treatment. We hypothesize that such impairment is explained by an age-related decrease in brain serotonin transporter (SERT) expression associated with low testosterone (T) levels. The object...

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Detalles Bibliográficos
Autores principales: Herrera-Pérez, José Jaime, Fernández-Guasti, Alonso, Martínez-Mota, Lucía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437264/
https://www.ncbi.nlm.nih.gov/pubmed/26317087
http://dx.doi.org/10.1155/2013/201909