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ASIC-dependent LTP at multiple glutamatergic synapses in amygdala network is required for fear memory

Genetic variants in the human ortholog of acid-sensing ion channel-1a subunit (ASIC1a) gene are associated with panic disorder and amygdala dysfunction. Both fear learning and activity-induced long-term potentiation (LTP) of cortico-basolateral amygdala (BLA) synapses are impaired in ASIC1a-null mic...

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Detalles Bibliográficos
Autores principales: Chiang, Po-Han, Chien, Ta-Chun, Chen, Chih-Cheng, Yanagawa, Yuchio, Lien, Cheng-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437300/
https://www.ncbi.nlm.nih.gov/pubmed/25988357
http://dx.doi.org/10.1038/srep10143