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Neuroprotection by Exendin-4 Is GLP-1 Receptor Specific but DA D(3) Receptor Dependent, Causing Altered BrdU Incorporation in Subventricular Zone and Substantia Nigra

Glucagon-like peptide-1 receptor (GLP-1R) activation by exendin-4 (EX-4) is effective in preclinical models of Parkinson's disease (PD) and appears to promote neurogenesis even in severely lesioned rats. In the present study, we determined the effects of EX-4 on cellular BrdU incorporation in t...

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Detalles Bibliográficos
Autores principales: Harkavyi, A., Rampersaud, N., Whitton, P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437329/
https://www.ncbi.nlm.nih.gov/pubmed/26316987
http://dx.doi.org/10.1155/2013/407152