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Glial Cell Line-Derived Neurotrophic Factor Family Members Reduce Microglial Activation via Inhibiting p38MAPKs-Mediated Inflammatory Responses

Previous studies have shown that glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL) are potent survival factors for dopaminergic neurons and motoneurons with therapeutic potential for Parkinson's disease. However, little is known about direct influences of the GFL on microg...

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Detalles Bibliográficos
Autores principales: Rickert, Uta, Grampp, Steffen, Wilms, Henrik, Spreu, Jessica, Knerlich-Lukoschus, Friederike, Held-Feindt, Janka, Lucius, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437344/
https://www.ncbi.nlm.nih.gov/pubmed/26317008
http://dx.doi.org/10.1155/2014/369468