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Valproic Acid Neuroprotection in the 6-OHDA Model of Parkinson's Disease Is Possibly Related to Its Anti-Inflammatory and HDAC Inhibitory Properties

Parkinson's disease is a neurodegenerative disorder where the main hallmark is the dopaminergic neuronal loss. Besides motor symptoms, PD also causes cognitive decline. Although current therapies focus on the restoration of dopamine levels in the striatum, prevention or disease-modifying therap...

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Detalles Bibliográficos
Autores principales: Ximenes, José Christian Machado, Neves, Kelly Rose Tavares, Leal, Luzia Kalyne A. M., do Carmo, Marta Regina Santos, Brito, Gerly Anne de Castro, Naffah-Mazzacoratti, Maria da Graça, Cavalheiro, Ésper Abrão, Viana, Glauce Socorro de Barros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437346/
https://www.ncbi.nlm.nih.gov/pubmed/26317011
http://dx.doi.org/10.1155/2015/313702