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Aquaporin-4 autoantibodies increase vasogenic edema formation and infarct size in a rat stroke model

BACKGROUND: Neuromyelitis optica (NMO) is an autoimmune disorder of the central nervous system, which is characterized by autoantibodies directed against the water channel aquaporin-4 (AQP4). As one of the main water regulators in the central nervous system, APQ4 is supposed to be involved in the dy...

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Detalles Bibliográficos
Autores principales: Juenemann, Martin, Braun, Tobias, Doenges, Simone, Nedelmann, Max, Mueller, Clemens, Bachmann, Georg, Singh, Pratibha, Blaes, Franz, Gerriets, Tibo, Tschernatsch, Marlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437448/
https://www.ncbi.nlm.nih.gov/pubmed/25986484
http://dx.doi.org/10.1186/s12865-015-0087-y