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Aquaporin-4 autoantibodies increase vasogenic edema formation and infarct size in a rat stroke model
BACKGROUND: Neuromyelitis optica (NMO) is an autoimmune disorder of the central nervous system, which is characterized by autoantibodies directed against the water channel aquaporin-4 (AQP4). As one of the main water regulators in the central nervous system, APQ4 is supposed to be involved in the dy...
Autores principales: | Juenemann, Martin, Braun, Tobias, Doenges, Simone, Nedelmann, Max, Mueller, Clemens, Bachmann, Georg, Singh, Pratibha, Blaes, Franz, Gerriets, Tibo, Tschernatsch, Marlene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437448/ https://www.ncbi.nlm.nih.gov/pubmed/25986484 http://dx.doi.org/10.1186/s12865-015-0087-y |
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