PSA-NCAM-Negative Neural Crest Cells Emerging during Neural Induction of Pluripotent Stem Cells Cause Mesodermal Tumors and Unwanted Grafts

Tumorigenic potential of human pluripotent stem cells (hPSCs) is an important issue in clinical applications. Despite many efforts, PSC-derived neural precursor cells (NPCs) have repeatedly induced tumors in animal models even though pluripotent cells were not detected. We found that polysialic acid...

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Detalles Bibliográficos
Autores principales: Lee, Dongjin R., Yoo, Jeong-Eun, Lee, Jae Souk, Park, Sanghyun, Lee, Junwon, Park, Chul-Yong, Ji, Eunhyun, Kim, Han-Soo, Hwang, Dong-Youn, Kim, Dae-Sung, Kim, Dong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437469/
https://www.ncbi.nlm.nih.gov/pubmed/25937368
http://dx.doi.org/10.1016/j.stemcr.2015.04.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437469/
https://www.ncbi.nlm.nih.gov/pubmed/25937368
http://dx.doi.org/10.1016/j.stemcr.2015.04.002

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