A single dose of dexamethasone encapsulated in polyethylene glycol-coated polylactic acid nanoparticles attenuates cisplatin-induced hearing loss following round window membrane administration

This study aimed to investigate the sustained drug release properties and hearing protection effect of polyethylene glycol-coated polylactic acid (PEG-PLA) stealth nanoparticles loaded with dexamethasone (DEX). DEX was fabricated into PEG-PLA nanoparticles using an emulsion and evaporation technique...

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Detalles Bibliográficos
Autores principales: Sun, Changling, Wang, Xueling, Zheng, Zhaozhu, Chen, Dongye, Wang, Xiaoqin, Shi, Fuxin, Yu, Dehong, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437605/
https://www.ncbi.nlm.nih.gov/pubmed/25999718
http://dx.doi.org/10.2147/IJN.S77912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437605/
https://www.ncbi.nlm.nih.gov/pubmed/25999718
http://dx.doi.org/10.2147/IJN.S77912

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