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Positive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade
Metabolic reprogramming plays an essential role in supporting the survival and proliferation of cancer cells. Serine hydroxymethyltransferase (SHMT) directs serine to the metabolism of one-carbon unit and the synthesis of thymidilate as a key factor in this metabolic shift. Although the mitochondria...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437609/ https://www.ncbi.nlm.nih.gov/pubmed/25999742 http://dx.doi.org/10.2147/OTT.S82433 |