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Elimination of HIV-1-Infected Primary T Cell Reservoirs in an In Vitro Model of Latency

Establishment of long-lived cellular reservoirs of HIV-1 represents a major therapeutic challenge to virus eradication. In this study, we utilized a human primary cell model of HIV-1 latency to evaluate the requirements for efficient virus reactivation from, and the selective elimination of, latentl...

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Detalles Bibliográficos
Autores principales: Rawlings, Stephen A., Alonzo, Francis, Kozhaya, Lina, Torres, Victor J., Unutmaz, Derya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437782/
https://www.ncbi.nlm.nih.gov/pubmed/25993666
http://dx.doi.org/10.1371/journal.pone.0126917