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TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption
Plekhm1 is a large, multi-modular, adapter protein implicated in osteoclast vesicle trafficking and bone resorption. In patients, inactivating mutations cause osteopetrosis, and gain-of-function mutations cause osteopenia. Investigations of potential Plekhm1 interaction partners by mass spectrometry...
Autores principales: | Witwicka, Hanna, Jia, Hong, Kutikov, Artem, Reyes-Gutierrez, Pablo, Li, Xiangdong, Odgren, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438057/ https://www.ncbi.nlm.nih.gov/pubmed/25992615 http://dx.doi.org/10.1371/journal.pone.0127537 |
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