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Base-CP proteasome can serve as a platform for stepwise lid formation

26S proteasome, a major regulatory protease in eukaryotes, consists of a 20S proteolytic core particle (CP) capped by a 19S regulatory particle (RP). The 19S RP is divisible into base and lid sub-complexes. Even within the lid, subunits have been demarcated into two modules: module 1 (Rpn5, Rpn6, Rp...

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Detalles Bibliográficos
Autores principales: Yu, Zanlin, Livnat-Levanon, Nurit, Kleifeld, Oded, Mansour, Wissam, Nakasone, Mark A., Castaneda, Carlos A., Dixon, Emma K., Fushman, David, Reis, Noa, Pick, Elah, Glickman, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438304/
https://www.ncbi.nlm.nih.gov/pubmed/26182356
http://dx.doi.org/10.1042/BSR20140173