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Continuous de novo biosynthesis of haem and its rapid turnover to bilirubin are necessary for cytoprotection against cell damage
It is well known that haem serves as the prosthetic group of various haemoproteins that function in oxygen transport, respiratory chain, and drug metabolism. However, much less is known about the functions of the catabolites of haem in mammalian cells. Haem is enzymatically degraded to iron, carbon...
Autores principales: | Takeda, Taka-aki, Mu, Anfeng, Tai, Tran Tien, Kitajima, Sakihito, Taketani, Shigeru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438432/ https://www.ncbi.nlm.nih.gov/pubmed/25990790 http://dx.doi.org/10.1038/srep10488 |
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