Pathogenic aquaporin-4 reactive T cells are sufficient to induce mouse model of neuromyelitis optica

INTRODUCTION: Neuromyelitis Optica (NMO) is an autoimmune disease primarily targeting the spinal cord and optic nerve leading to paralysis and blindness. The discovery of an antibody against the astrocytic water channel, aquaporin-4 (AQP4), in the majority of patients, has led to the presumption tha...

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Detalles Bibliográficos
Autores principales: Jones, Melina V., Huang, Hwa, Calabresi, Peter A., Levy, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438510/
https://www.ncbi.nlm.nih.gov/pubmed/25990016
http://dx.doi.org/10.1186/s40478-015-0207-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438510/
https://www.ncbi.nlm.nih.gov/pubmed/25990016
http://dx.doi.org/10.1186/s40478-015-0207-1

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