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CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation

BACKGROUND: Chemokines and chemokine receptors cooperate to promote immune cell recruitment to the central nervous system (CNS). In this study, we investigated the roles of CXCR2 and CXCL1 in leukocyte recruitment to the CNS using a murine model of neuroinflammation. METHODS: Wild-type (WT), CXCL1(−...

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Detalles Bibliográficos
Autores principales: Wu, Fengjiao, Zhao, Yawei, Jiao, Tian, Shi, Dongyan, Zhu, Xingxing, Zhang, Mingshun, Shi, Meiqing, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438521/
https://www.ncbi.nlm.nih.gov/pubmed/25990934
http://dx.doi.org/10.1186/s12974-015-0316-6