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CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation
BACKGROUND: Chemokines and chemokine receptors cooperate to promote immune cell recruitment to the central nervous system (CNS). In this study, we investigated the roles of CXCR2 and CXCL1 in leukocyte recruitment to the CNS using a murine model of neuroinflammation. METHODS: Wild-type (WT), CXCL1(−...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438521/ https://www.ncbi.nlm.nih.gov/pubmed/25990934 http://dx.doi.org/10.1186/s12974-015-0316-6 |