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Bimodal Effect of Lithium Plasma Levels on Hippocampal Glutamate Concentrations in Bipolar II Depression: A Pilot Study

BACKGROUND: The hippocampus has been highly implicated in the pathophysiology of bipolar disorder (BD). Nevertheless, no study has longitudinally evaluated hippocampal metabolite levels in bipolar depression under treatment with lithium. METHODS: Nineteen medication-free BD patients (78.9% treatment...

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Detalles Bibliográficos
Autores principales: Zanetti, Marcus V., Otaduy, Maria C., de Sousa, Rafael T., Gattaz, Wagner F., Busatto, Geraldo F., Leite, Claudia C., Machado-Vieira, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438538/
https://www.ncbi.nlm.nih.gov/pubmed/25522399
http://dx.doi.org/10.1093/ijnp/pyu058