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Toll-Like Receptor Expression in the Blood and Brain of Patients and a Mouse Model of Parkinson’s Disease

BACKGROUND: Accumulating evidence supports a role for the immune system in the pathogenesis of Parkinson’s disease. Importantly, recent preclinical studies are now suggesting a specific contribution of inflammation to the α-synuclein-induced pathology seen in this condition. METHODS: We used flow cy...

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Detalles Bibliográficos
Autores principales: Drouin-Ouellet, Janelle, St-Amour, Isabelle, Saint-Pierre, Martine, Lamontagne-Proulx, Jérôme, Kriz, Jasna, Barker, Roger A., Cicchetti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438545/
https://www.ncbi.nlm.nih.gov/pubmed/25522431
http://dx.doi.org/10.1093/ijnp/pyu103