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Identification of targets for rational pharmacological therapy in childhood craniopharyngioma

INTRODUCTION: Pediatric adamantinomatous craniopharyngioma (ACP) is a histologically benign but clinically aggressive brain tumor that arises from the sellar/suprasellar region. Despite a high survival rate with current surgical and radiation therapy (75–95 % at 10 years), ACP is associated with deb...

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Detalles Bibliográficos
Autores principales: Gump, Jacob M., Donson, Andrew M., Birks, Diane K., Amani, Vladimir M., Rao, Karun K., Griesinger, Andrea M., Kleinschmidt-DeMasters, B. K., Johnston, James M., Anderson, Richard C. E., Rosenfeld, Amy, Handler, Michael, Gore, Lia, Foreman, Nicholas, Hankinson, Todd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438576/
https://www.ncbi.nlm.nih.gov/pubmed/25990246
http://dx.doi.org/10.1186/s40478-015-0211-5