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Anti-CCL2: building a reservoir or opening the floodgates to metastasis?

Neutralisation of macrophage chemoattractant C-C chemokine ligand 2 (CCL2) has shown reduced metastasis and enhanced survival in numerous experimental models of tumorigenesis. However, important new findings reported in Nature by Momo Bentires-Alj’s laboratory demonstrate that withdrawal of anti-CCL...

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Detalles Bibliográficos
Autores principales: Hitchcock, Jessica R, Watson, Christine J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438584/
https://www.ncbi.nlm.nih.gov/pubmed/25990313
http://dx.doi.org/10.1186/s13058-015-0573-4