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PRKACA: the catalytic subunit of protein kinase A and adrenocortical tumors

Cyclic-AMP (cAMP)-dependent protein kinase (PKA) is the main effector of cAMP signaling in all tissues. Inactivating mutations of the PRKAR1A gene, coding for the type 1A regulatory subunit of PKA, are responsible for Carney complex and primary pigmented nodular adrenocortical disease (PPNAD). PRKAR...

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Detalles Bibliográficos
Autores principales: Berthon, Annabel S., Szarek, Eva, Stratakis, Constantine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438593/
https://www.ncbi.nlm.nih.gov/pubmed/26042218
http://dx.doi.org/10.3389/fcell.2015.00026